Giants lose to San Francisco 27-20.
Eli Manning was 26 of 40 for 311 yards with 2 TDs and 2 INTs.
Brandon Jacobs rushed for 55 yards on 18 carries and had 2 catches for 17 yards.
Danny Ware rushed for 34 yards on 9 carries and had 5 catches for 34 yards.
Victor Cruz caught 6 passes for 84 yards.
Mario Manningham caught 6 passes for 77 yards and 1 TD.
Hakeem Nicks caught 2 passes for 41 yards and 1 TD.
Jake Ballard caught 3 passes for 35 yards.
Bear Pascoe caught 2 passes for 23 yards.
Corey Webster had 1 interception.
Osi Umenyiora and Linval Joseph each had 1 sack.
Lawrence Tynes kicked field goals of 23 and 35 yards.

Game Notes:
"The opening drive got the Giants down to the Niners 5 yard line, but they had to settle for a field goal on 4th and 2. I didn't know then that settling for field goals would be the course of the game for the whole first half for both teams, but that's what happened and it continued into the third quarter before the Giants finally broke out with a touchdown pass to Mario Manningham for a 13-12 lead. I was glad to see early on that the Giants could run on the Niners tough defensive unit but was also unhappy that their quarterback, Alex Smith, could throw on ours. Sure it was great that our defense could stop the Niners running game, but at what cost?
I have to say that Mikefan called it in his game preview 'The Giants are gearing up for Frank Gore's rushing attack, even changing some personnel on their defense. Gore was hurt last week and this could be a spot for the Niners to break out with a clever passing strategy knowing they might catch the Giants literally 'flat-footed' in that area. At some point the 49ers need to see if they can manage a more balanced run-pass offense that can take them somewhere in the playoffs as they move forward. Could this be the week?' Well this was the week and San Francisco was able to make it stick!"

Game Notes:
"Losing Michael Boley in the first half was a big blow. He's a great influence, relaying calls into the huddle, and this week especially so since the Giants were fielding rookie Greg Jones, expecting to see a lot of runs coming their way. Aside from the obvious mistakes made by the special teams unit, I would say it was a big reason the Giants lost this one. As to San Francisco's pass oriented game switch, I'd say if the head coach is calling his untested quarterback 'elite' to the press in the week right before the game, you should guess that he might be excited about his plans. That's one of the reasons I mentioned it in the game preview.
At the end of the half, Eli Manning was 13 of 18 for 121 yards and 1 Interception and Alex Smith was every bit matching him, 12 of 17 for 151 yards and 1 interception. Smith had also done the major running for the Niners. Running back Frank Gore had zero yards on 6 carries, and Smith had 2 scrambles for 26 yards. Gore became a non factor and his team record of five straight games with 100 yards rushing ended because he later suffered a knee injury.
Gore was replaced by Kendall Hunter who was actually more effective, and Alex Smith kept his team moving. They scored two touchdowns to the Giants one in the last quarter as Eli Manning can't always lead the team to a come from behind victory in every game that's played. He sure tried his best making a 4th and 5 and then a 4th and 2 before falling short on the 49ers 10 yard line on yet another 4th and 2 when the ball was batted down."

Giants Eli Manning started with 10 completions on 10 passes, the best start of his career.

Giants held the 49ers to just 77 rushing yards, the first time they finished under 100 since the season opener.

San Francisco made their first two point conversion of the season.

San Francisco now has a seven game winning streak.

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