Giants lose to San Francisco 16-10.
Eli Manning was 22 of 45 for 280 yards with 5 INTs and 1TD.
Rashad Jennings rushed for 59 yards on 18 carries and caught 4 passes for 8 yards.
Henry Hynoski rushed for 4 yards on 1 carry.
Andre Williams rushed for 2 yards on 2 carries and caught 1 pass for 4 yards.
Rueben Randle caught 7 passes for 112 yards.
Odell Beckham Jr. caught 6 passes for 93 yards.
Larry Donnell caught 3 pass for 54 yards.
Preston Parker caught 1 passes for 9 yards.
Robert Ayers had 1 sack.
Josh Brown kicked a 43 yard field goal and recovered an onside punt.

Game Notes:
"This was a nail biting game that kept fans in their seats to the end. It's hard to believe that the Giants defense gave up only 16 points and we lost. Then again it's also hard to believe that Eli Manning threw 5 interceptions and we lost by just 6 points. This should have been a blowout for the 49ers, but the Giants even led at the start and were never down by more than nine points at any time.
In the middle of the third quarter the Giants cut that to six points when Josh Brown kicked a 43 yard field goal and then followed up with an onside kick that the Giants recovered. Things were going our way and you got the feeling that the Giants were going to win this one. That feeling sunk a bit when Rashad Jennings got nowhere and on third down Manning threw another interception.
Still the defense held them to no points on that drive, and impressively the rest of the third quarter and all of the fourth. Right tackle Justin Pugh had left the game much earlier, and Jennings was just back playing for the first time in a long while, so I guess that didn't help Manning from being more predicable or comfortable against the 49er defense.
With this loss, that puts the Giants at 3-7 and the other teams in the NFC East will have to collapse for them to have a playoff shot. As a fan, all I can say is that the Giants will have to do their part, beginning next week against the Cowboys in MetLife Stadium."

Game Notes:
"It's interesting that the final yardage numbers for San Francisco and the Giants were about the same. Quarterback Colin Kaepernick (15 of 29) and Eli Manning (22 of 45) had about the same completion percentage, with Kaepernick throwing for 80 less yards, but with no costly mistakes. The 49er running game, assisted by Kaepernick, made up for those yards as both teams had about the same total - Giants 330, 49ers 333.
The mistakes made all the difference, but the Giants almost overcame them and could have won this game. Close, as they say (if you're old enough) but no cigar. With five minutes left the Giants had four chances to go ahead if they could punch the ball in from the San Francisco 4 yard line, but couldn't make that happen. Actually there were no rushing attempts to 'punch the anything in'. Manning threw three incomplete passes and then threw his fifth interception, which would not have happened if any of the other three plays got them in the endzone. That interception actually cost the 49ers two yards, as the ball would have been theirs at the four yard line instead of the two if it was knocked down by the defender instead.
It would have been great if the Giants defense could have gotten a three and out, but that was going to the well one too many times after the day they put in today. Frank Gore got his 49ers away from the two yard line with two runs, resulting in a first down, to give them some working room. By the time the 49er drive ended with a punt, the Giants got the ball back at their own 15 yard line with a little more than a minute left.
This is where Manning, your comeback quarterback, can shine in the final seconds to make things right, but again you have to be old enough to remember the Giants going way way back to yesteryear, in 2011. Your current memory is of Odell Beckham Jr. laying on the ground for a moment, then getting up and ripping his helmet off in frustration and throwing it down after almost catching a 4th-and-6 pass from Manning to keep their final drive going. Once again, close but no cigar."

Giants recovered an onside kick, their first successful onside kick since 2004.

Giants kicker Josh Brown was credited with his first career forced fumble.

Giants Rueben Randle had 7 receptions for his new career high of 112 yards.

Giants scored a touchdown on their opening drive for the first time in 20 games.

Giants are 0-6 when they win the coin toss and defer.

Giants Eli Manning tied his career high of 5 interceptions after having just 6 all season.

Giants 3-7 record after 10 games is their worst since 1998 (Jim Fassel), but they finished 8-8.

San Francisco is 21-9 in road games played under head coach Jim Harbaugh.

San Francisco is first in the NFL in road wins since 2011 when Jim Harbaugh took over.

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